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October 2008 - Breast Cancer Awareness Month What is the meaning of the Pink Ribbon |
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Lobular carcinoma in situ, or LCIS, is generally considered to be a pre-cancerous condition.
The term, lobular carcinoma in situ (LCIS), is misleading. This
lesion is more appropriately termed lobular neoplasia. Strictly
speaking, it is not known to be a premalignant lesion, but
rather a marker that identifies women at an increased risk for
subsequent development of invasive breast cancer. This risk
remains elevated even beyond 2 decades, and most of the
subsequent cancers are ductal rather than lobular. LCIS is
usually multicentric and is frequently bilateral. It is lobular because the cancer is confined to the lobules which are the glands that actually make milk. Carcinoma refers to any cancer that begins in the skin or other tissues that cover internal organs—such as breast tissue. In situ or "in its original place" means that the cancer has not spread to any surrounding tissues. The graphic shown below is of a normal breast with lobular carcinoma in situ (LCIS) presented in the enlarged section.
Breast profile: [A] Ducts
[B] Lobules
[C] Dilated section of milk duct Enlargement: [A] Normal lobular cells
[B] Lobular cancer cells
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Common Presentations |
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Breast Self Examination |